Search results for "Lactobacillus johnsonii"

showing 3 items of 3 documents

Human milk and mucosal lacto- and galacto-N-biose synthesis by transgalactosylation and their prebiotic potential in Lactobacillus species.

2017

Lacto-N-biose (LNB) and galacto-N-biose (GNB) are major building blocks of free oligosaccharides and glycan moieties of glyco-complexes present in human milk and gastrointestinal mucosa. We have previously characterized the phospho-β-galactosidase GnbG from Lactobacillus casei BL23 that is involved in the metabolism of LNB and GNB. GnbG has been used here in transglycosylation reactions, and it showed the production of LNB and GNB with N-acetylglucosamine and N-acetylgalactosamine as acceptors, respectively. The reaction kinetics demonstrated that GnbG can convert 69 ± 4 and 71 ± 1 % of o-nitrophenyl-β-d-galactopyranoside into LNB and GNB, respectively. Those reactions were performed in a s…

0301 basic medicineGlycanLactobacillus caseiTransglycosylationAcetylgalactosamineGlycosylationMagnetic Resonance SpectroscopyGlycoside Hydrolasesmedicine.medical_treatment030106 microbiologyMicrobiologiaPrebioticBiologyLactobacillus gasseriDisaccharidesApplied Microbiology and BiotechnologyMicrobiologyAcetylglucosamine03 medical and health sciencesLactobacillus rhamnosusmedicineIntestinal MucosaGalacto-N-bioseLactobacillus johnsoniiMilk HumanPrebioticHuman milk oligosaccharidesfood and beveragesNucleic Acid HybridizationGeneral MedicineMetabolismbiology.organism_classificationLactobacilsKineticsLactobacillus030104 developmental biologyPrebioticsBiochemistrybiology.proteinFermentationLacto-N-bioseBiotechnologyApplied microbiology and biotechnology
researchProduct

H89 Treatment Reduces Intestinal Inflammation and Candida albicans Overgrowth in Mice

2020

Deregulation of the dynamic crosstalk between the gut microbiota, intestinal epithelial cells, and immune cells is critically involved in the development of inflammatory bowel disease and the overgrowth of opportunistic pathogens, including the human opportunistic fungus Candida albicans. In the present study, we assessed the effect of N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H89), a protein kinase A inhibitor, on the migration of macrophages to C. albicans through dextran sulphate sodium (DSS)-challenged Caco-2 cells. We also investigated the impact of H89 on intestinal inflammation and C. albicans clearance from the gut, and determined the diversity of the gut microbio…

0301 basic medicineMicrobiology (medical)<i>Lactobacillus johnsonii</i>colitisH89030106 microbiologyInflammationGut floraMicrobiologydigestive systemArticleMicrobiology03 medical and health sciences<i>Enterococcus faecalis</i>Immune system[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesVirologyCandida albicansmedicineEscherichia coliEnterococcus faecalismicrobiotaColitisCandida albicanslcsh:QH301-705.5Lactobacillus johnsoniiLactobacillus johnsoniiDSSH89;Candida albicans;Escherichia coli;Enterococcus faecalis;Lactobacillus johnsonii;microbiota;DSS;colitis;protein kinase AInnate immune systembiology<i>Escherichia coli</i>[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologymedicine.diseasebiology.organism_classificationCorpus albicans3. Good health<i>Candida albicans</i>030104 developmental biologylcsh:Biology (General)[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacologyprotein kinase Amedicine.symptomMicroorganisms
researchProduct

Probiotic Potential of Leuconostoc pseudomesenteroides and Lactobacillus Strains Isolated From Yaks

2018

The purpose of this study was to evaluate the antibacterial activity and safety of bacterias with probiotic potential isolated from free-ranging Tibetan yaks in high altitude regions of Tibet. For this purpose, one Leuconostoc pseudomesenteroides strain (named P1) and two Lactobacillus johnsonii and Lactobacillus mucosae strains (named LY1 and LY2), respectively, were isolated from fecal samples of Tibetan yaks. The antibacterial activity of the isolates was studied using Escherichia coli (E. coli ATCC 25922), Staphylococcus aureus (S. aureus ATCC 26112), and Salmonella enteritidis (S. enteritidis NCTC 13349) as indicator pathogens. The results showed that LY1 had high antibacterial efficac…

0301 basic medicineMicrobiology (medical)safetySalmonella enteritidis030106 microbiologyLactobacillus mucosaelcsh:QR1-502Leuconostoc pseudomesenteroidesBiologymedicine.disease_causeMicrobiologyLeuconostoc pseudomesenteroideslcsh:MicrobiologyMicrobiologylaw.invention03 medical and health sciencesProbioticantibacterial activitylawLactobacillusmedicineEscherichia coliLactobacillus johnsoniiOriginal Researchbiology.organism_classification030104 developmental biologyyaksStaphylococcus aureusLactobacillus strainsFrontiers in Microbiology
researchProduct